Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

TNF-α Pretreatment Improves the Survival and Function of Transplanted Human Neural Progenitor Cells Following Hypoxic-Ischemic Brain Injury.

Cells - 11 May 2020

Kim Miri, Jung Kwangsoo, Ko Younhee, Kim Il-Sun, Hwang Kyujin, Jang Jae-Hyung, Shin Jeong Eun, Park Kook In

Abstract excerpt

Neural progenitor cells (NPCs) therapy offers great promise in hypoxic-ischemic (HI) brain injury. However, the poor survival of implanted NPCs in the HI host environment limits their therapeutic effects. Tumor necrosis factor-alpha (TNF-α) is a pleiotropic cytokine that is induced in response to a variety of pathological processes including inflammation and immunity. On the other hand, TNF-α has protective...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain Injuries
Share to Caspase 3

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Culture Media, Conditioned

Share to Hypoxia-Ischemia, Brain

Share to Mice, Inbred ICR

Share to Nerve Growth Factors

Share to Neural Stem Cells

Share to Neuroprotection

Source

Open in PubMed Open full text

Identifiers

PMID: 32403417
DOI: 10.3390/cells9051195
PMCID: PMC7291333

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

TNF-α Pretreatment Improves the Survival and Function of Transplanted Human Neural Progenitor Cells Following Hypoxic-Ischemic Brain Injury.PMID 32403417Read ↗

TNF-α respecifies human mesenchymal stem cells to a neural fate and promotes migration toward experimental glioma.Semantic proximity Read ↗

Mutated IkappaBalpha represses proliferation of immortalized neural progenitor cells and prevents their apoptosis after oxygen-glucose deprivation.Semantic proximity Read ↗

NF-κB and TNF Affect the Astrocytic Differentiation from Neural Stem Cells.Semantic proximity Read ↗

Human umbilical cord mesenchymal stem cells alleviate white-matter injury by regulating polarization of microgliaSemantic proximity Read ↗

Time-dependent changes in the microenvironment of injured spinal cord affects the therapeutic potential of neural stem cell transplantation for spinal cord injury.Semantic proximity Read ↗

Effects of human umbilical cord mesenchymal stem cell (hUC-MSC)-derived exosomes on HIBD immunoinflammation in neonatal ratsSemantic proximity Read ↗

Delayed Treatment with Green Tea Polyphenol EGCG Promotes Neurogenesis After Ischemic Stroke in Adult Mice.Semantic proximity Read ↗

Glutamate Increases In Vitro Survival and Proliferation and Attenuates Oxidative Stress-Induced Cell Death in Adult Spinal Cord-Derived Neural Stem/Progenitor Cells via Non-NMDA Ionotropic Glutamate Receptors.Semantic proximity Read ↗

Human umbilical cord blood mononuclear cells and chorionic plate-derived mesenchymal stem cells promote axon survival in a rat model of optic nerve crush injury.Semantic proximity Read ↗

Cellular therapy for traumatic neurological injury.Semantic proximity Read ↗

Quieting the Storm: Hypoxia as a Strategy to Boost UC-MSC Therapies for Neonatal Hypoxic-Ischemic EncephalopathySemantic proximity Read ↗

N‐Acetylcysteine Treats Spinal Cord Injury by Inhibiting Astrocyte ProliferationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.