Article
Mutated IkappaBalpha represses proliferation of immortalized neural progenitor cells and prevents their apoptosis after oxygen-glucose deprivation.
Brain research - 9 Dec 2008
Zhu Chang, Liu Zhiheng, Gui Lingli, Yao Wenlong, Qian Wei, Zhang Chuanhan
Abstract excerpt
Endogenic and transplanted neural progenitor cells (NPCs) can be activated by cerebral ischemia and take part in the regeneration of neural function. NF-kappaB was found activated in the same pathology procedure and was assumed to play a crucial role in regulating NPCs' physiology. But it is still not clear whether NF-kappaB is activated in NPCs in cerebral ischemia and what is the effect of NF-kappaB on NPCs...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
