Article
The 5-HTTLPR long allele predicts two-year longitudinal increases in cortisol and declines in verbal memory in older adults.
International journal of geriatric psychiatry - 1 Sept 2020
Hirst Rayna B, Jordan Joshua T, Schüssler-Fiorenza Rose Sophia Miryam, Schneider Logan, Kawai Makoto, Gould Christine E, Anker Lauren, Chick Christina F, Beaudreau Sherry A, Hallmayer Joachim, O'Hara Ruth
Abstract excerpt
OBJECTIVES: The short form or s-allele variant of the serotonin transporter polymorphism (5-HTTLPR), as compared with the long-form or l-allele variant, has been associated with the presence of cognitive dysfunction, and particularly memory impairment in older adults. This body of cross-sectional work has culminated in the hypothesis that presence of the s-allele predicts greater memory decline in older adults....
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