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Article

5-HTTLPR short allele, resilience, and successful aging in older adults.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry - 1 May 2012

OʼHara Ruth, Marcus Peter, Thompson Wesley K, Flournoy John, Vahia Ipsit, Lin Xiaoyan, Hallmayer Joachim, Depp Colin, Jeste Dilip V

Abstract excerpt

OBJECTIVE: Resilience is proposed as a significant component of successful aging. Young adult carriers of the Serotonin Transporter Polymorphism (5-HTTLPR) short(s) allele appear to have reduced resilience to stress. We examined whether the presence of the short allele was associated with poorer emotional resilience in older adults. METHODS: In a cross-sectional study of 99 healthy, community-dwelling, older...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22233775
DOI: 10.1097/JGP.0b013e31823e2d03
PMCID: PMC3326186

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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