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Dual Role of Autophagy in Regulation of Mesenchymal Stem Cell Senescence

24 Apr 2020

Abstract excerpt

During their development and overall life, mesenchymal stem cells (MSCs) encounter a plethora of internal and external stress signals and therefore, they need to put in action homeostatic changes in order to face these stresses. To this aim, similar to other mammalian cells, MSCs are endowed with two crucial biological responses, autophagy and senescence. Sharing of a number of stimuli like shrinkage of...

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PMID: 32391362
DOI: 10.3389/fcell.2020.00276

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