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Article

Autophagy in stem cell aging

7 Aug 2017

Abstract excerpt

Aging is responsible for changes in mammalian tissues that result in an imbalance to tissue homeostasis and a decline in the regeneration capacity of organs due to stem cell exhaustion. Autophagy is a constitutive pathway necessary to degrade damaged organelles and protein aggregates. Autophagy is one of the hallmarks of aging, which involves a decline in the number and functionality of stem cells. Recent studies...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 28782921
DOI: 10.1111/acel.12655

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