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Autophagy at the intersection of aging, senescence, and cancer

11 Jun 2022

Abstract excerpt

Autophagy is an evolutionarily conserved cellular process in which macromolecules undergo lysosomal degradation. It fulfills essential roles in quality controlling cellular constituents and in energy homeostasis. Basal autophagy is also widely accepted to provide a protective role in aging and aging-related disorders, and its decline with age might precipitate the onset of a variety of diseases. In this review,...

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PMID: 35689420
DOI: 10.1002/1878-0261.13269

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