Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pharmacokinetic Parameters of HIV-1 Protease Inhibitors.

ChemMedChem - 17 Jun 2020

Nascimento André L C S, Fernandes Richard P, Quijia Christian, Araujo Victor H S, Pereira Juliana, Garcia Jerusa S, Trevisan Marcello G, Chorilli Marlus

Abstract excerpt

Since the beginning of the HIV epidemic, research has been carried out to control the virus. Understanding the mechanisms of replication has given access to the various classes of drugs that over time have transformed AIDS into a manageable chronic disease. The class of protease inhibitors (PIs) gained notice in anti-retroviral therapy, once it was found that peptidomimetic molecules act by blocking the active...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytochrome P-450 Enzyme Inhibitors
Share to Drug Resistance, Viral

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to HIV Protease

Share to HIV Protease Inhibitors

Share to Mutation

Source

Identifiers

PMID: 32390304
DOI: 10.1002/cmdc.202000101

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pharmacokinetic Parameters of HIV-1 Protease Inhibitors.PMID 32390304Read ↗

Current and Novel Inhibitors of HIV ProteaseSemantic proximity Read ↗

Comprehending the Structure, Dynamics, and Mechanism of Action of Drug-Resistant HIV ProteaseSemantic proximity Read ↗

HIV Protease: Historical Perspective and Current ResearchSemantic proximity Read ↗

Navigating HIV-1 drug resistance: A comprehensive review of protease inhibitor efficacy and mutation dynamics.Semantic proximity Read ↗

Recent developments in HIV protease inhibitor therapy.Semantic proximity Read ↗

Structural and dynamical aspects of HIV-1 protease and its role in drug resistance.Semantic proximity Read ↗

Investigation of molecular mechanisms regulating drug-drug interactions in antiretroviral therapySemantic proximity Read ↗

Design of novel HIV-1 protease inhibitors with favorable oral properties using a virtual screening and lead optimization approachSemantic proximity Read ↗

Principles and practice of HIV-protease inhibitor pharmacoenhancement.Semantic proximity Read ↗

HIV protease: enzyme function and drug resistance.Semantic proximity Read ↗

Pharmacological outlook of Lenacapavir: a novel first-in-class Long-Acting HIV-1 Capsid InhibitorSemantic proximity Read ↗

The pharmacokinetics, pharmacodynamics and pharmacogenetics of Dolutegravir and Cobicistat in the treatment of HIVSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.