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An investigation of the relationship between TMPRSS6 gene expression, genetic variants and clinical findings in breast cancer.

Molecular biology reports - 1 Jun 2020

Mete Meltem, Trabulus Didem Can, Talu Canan Kelten, Ozoran Emre, Mutlu Tuba, Tekin Bulent, Guven Mehmet

Abstract excerpt

Breast cancer is one of the most common types of cancer among women worldwide. The TMPRSS6 (Transmembrane Serine Protease 6) gene encodes matriptase-2, which plays an important role in iron hemostasis as the hepcidin regulator and may play a role in breast cancer susceptibility. In this study, we examined the expression levels of the TMPRSS6 gene in healthy tissues and tumor tissues of breast cancer patients; and...

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Identifiers

PMID: 32385772
DOI: 10.1007/s11033-020-05498-0

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