Article
Circulating Protein Signatures and Causal Candidates for Type 2 Diabetes.
Diabetes - 1 Aug 2020
Gudmundsdottir Valborg, Zaghlool Shaza B, Emilsson Valur, Aspelund Thor, Ilkov Marjan, Gudmundsson Elias F, Jonsson Stefan M, Zilhão Nuno R, Lamb John R, Suhre Karsten, Jennings Lori L, Gudnason Vilmundur
Abstract excerpt
The increasing prevalence of type 2 diabetes poses a major challenge to societies worldwide. Blood-based factors like serum proteins are in contact with every organ in the body to mediate global homeostasis and may thus directly regulate complex processes such as aging and the development of common chronic diseases. We applied a data-driven proteomics approach, measuring serum levels of 4,137 proteins in 5,438...
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