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The causal relationship between plasma protein-to-protein ratios and type 2 diabetes and its complications: Proteomics mendelian randomization study.

Diabetes, obesity & metabolism - 1 Oct 2024

Zhang Yue-Yang, Chen Bing-Xue, Yang Qin, Wan Qin

Abstract excerpt

AIM: In recent years, proteomics research has surged, with numerous observational studies identifying associations between plasma proteins and type 2 diabetes. However, research specifically focusing on the ratios of plasma proteins in type 2 diabetes remains relatively scarce. METHODS: This study primarily employed a two-sample, two-step Mendelian randomization (MR) approach, leveraging genetic data from several...

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Blood Proteins
Body Mass Index
Diabetes Complications
Diabetes Mellitus, Type 2
Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mendelian Randomization Analysis

Polymorphism, Single Nucleotide

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Identifiers

PMID: 39021342
DOI: 10.1111/dom.15792

Genes

CNTN3
DBNL
NCK2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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