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Understanding alveolarization to induce lung regeneration

6 Aug 2018

Abstract excerpt

BACKGROUND: Gas exchange represents the key physiological function of the lung, and is dependent upon proper formation of the delicate alveolar structure. Malformation or destruction of the alveolar gas-exchange regions are key histopathological hallmarks of diseases such as bronchopulmonary dysplasia (BPD), chronic obstructive pulmonary disease (COPD), and pulmonary fibrosis; all of which are characterized by...

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PMID: 30081910
DOI: 10.1186/s12931-018-0837-5

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