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Article

Identifying the HLA DRB1-DQB1 molecules and predicting epitopes associated with high-risk HPV infection clearance and redetection.

Scientific reports - 29 Apr 2020

Del Río-Ospina Luisa, Camargo Milena, Soto-De León Sara C, Sánchez Ricardo, Moreno-Pérez Darwin A, Patarroyo Manuel E, Patarroyo Manuel A

Abstract excerpt

Several determining factors are involved in HPV infection outcomes; human leukocyte antigen (HLA) polymorphisms have been described as related factors. This study has ascertained the effect of genetic variation on HLA-DRB1 and DQB1 genes on HPV-16/-18/-31/-33/-45 and -58 clearance and redetection in Colombian women. PCR and qPCR were used for viral identification and the Illumina MiSeq system was used for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32350356
DOI: 10.1038/s41598-020-64268-x
PMCID: PMC7190668

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