Article
Identifying HLA DRB1-DQB1 alleles associated with Chlamydia trachomatis infection and in silico prediction of potentially-related peptides.
Scientific reports - 18 Jun 2021
Pedraza Leidy, Camargo Milena, Moreno-Pérez Darwin A, Sánchez Ricardo, Del Río-Ospina Luisa, Báez-Murcia Indira M, Patarroyo Manuel E, Patarroyo Manuel A
Abstract excerpt
HLA class II (HLA-II) genes' polymorphism influences the immune response to Chlamydia trachomatis (Ct), it is considered a sexually transmitted infection. However, associations between HLA-II alleles and Ct-infection have been little explored in humans; this study was thus aimed at determining HLA-DRB1-DQB1 alleles/haplotypes' effect on Ct-infection outcome in a cohort of Colombian women. Cervical sample DNA was...
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