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Article

Genetic Variability and Conserved T-Cell Epitope Prediction of the HPV16 E1 Protein in Cervix Samples from Peru.

Pathogens (Basel, Switzerland) - 13 May 2026

Bonifacio-Velez de Villa Eliezer, Aguilar-Luis Miguel Angel, Silva-Caso Wilmer, Becerra-Goicochea Lorena, Tarazona-Castro Yordi, Aguilar-Luis Deysi, Denegri-Hinostroza Dayana, Cornejo-Tapia Angela, Aquino-Ortega Ronald, Del Valle-Mendoza Juana

Abstract excerpt

BACKGROUND: HPV16 is the most prevalent high-risk genotype associated with cervical cancer, yet the genetic variability and immune potential of the replication protein E1 are less characterized in asymptomatic infections. We assessed HPV16 E1 diversity and predicted conserved T-cell epitopes. METHODS: We conducted a descriptive cross-sectional study of cervical samples from women undergoing HPV screening. HPV was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42198652
DOI: 10.3390/pathogens15050526
PMCID: PMC13209587

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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