Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Integrative Transcriptome Analyses of the Human Fallopian Tube: Fimbria and Ampulla—Site of Origin of Serous Carcinoma of the Ovary

27 Apr 2020

Abstract excerpt

Epithelial ovarian cancer represents a group of heterogeneous diseases with high grade serous cancer (HGSC) representing the most common histotype. Molecular profiles of precancerous lesions found in the fallopian tube have implicated this tissue as the presumptive site of origin of HGSC. Precancerous lesions are primarily found in the distal fallopian tube (fimbria), near the ovary relative to the proximal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ovarian cancer diagnosis and treatment
Share to Reproductive Biology and Fertility
Share to Reproductive System and Pregnancy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32349388
DOI: 10.3390/cancers12051090

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Integrative Transcriptome Analyses of the Human Fallopian Tube: Fimbria and Ampulla—Site of Origin of Serous Carcinoma of the OvaryPMID 32349388Read ↗

A molecular atlas of the human postmenopausal fallopian tube and ovary from single-cell RNA and ATAC sequencingSemantic proximity Read ↗

A Cellular atlas of the human fallopian tube reveals the metamorphosis of secretory epithelial cells during the menstrual cycle and menopauseSemantic proximity Read ↗

Lessons from BRCA: the tubal fimbria emerges as an origin for pelvic serous cancer.Semantic proximity Read ↗

Rete Ovarii Epithelial Cells as an Unappreciated Cell of Origin for Pelvic and Ovarian High-Grade Serous CarcinomaSemantic proximity Read ↗

Mutant p53 disrupts antioxidant defense in fallopian tube epithelium via GSTAs suppression: A pathway to serous tubal carcinogenesis.Semantic proximity Read ↗

BRCA and Early Events in the Development of Serous Ovarian CancerSemantic proximity Read ↗

3D multi-omic mapping of whole nondiseased human fallopian tubes at cellular resolution reveals a large incidence of ovarian cancer precursorsSemantic proximity Read ↗

Single-cell transcriptomics identifies gene expression networks driving differentiation and tumorigenesis in the human fallopian tubeSemantic proximity Read ↗

From fallopian tube epithelium to high-grade serous ovarian cancer: A single-cell resolution review of sex steroid hormone signalingSemantic proximity Read ↗

WNT and inflammatory signaling distinguish human Fallopian tube epithelial cell populationsSemantic proximity Read ↗

Comparative single-cell atlases reveal injury-driven tubal epithelial regeneration as a window for ovarian carcinoma initiationSemantic proximity Read ↗

Single-cell Transcriptomics Identifies Gene Expression Networks Driving Differentiation and Tumorigenesis in the Human Fallopian TubeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.