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Article

LncGBP9/miR-34a axis drives macrophages toward a phenotype conducive for spinal cord injury repair via STAT1/STAT6 and SOCS3.

Journal of neuroinflammation - 28 Apr 2020

Zhou Jiahui, Li Zhiyue, Wu Tianding, Zhao Qun, Zhao Qiancheng, Cao Yong

Abstract excerpt

BACKGROUND: Acute spinal cord injury (SCI) could cause mainly two types of pathological sequelae, the primary mechanical injury, and the secondary injury. The macrophage in SCI are skewed toward the M1 phenotype that might cause the failure to post-SCI repair. METHODS: SCI model was established in Balb/c mice, and the changes in macrophage phenotypes after SCI were monitored. Bioinformatic analyses were performed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 32345320
DOI: 10.1186/s12974-020-01805-5
PMCID: PMC7187522

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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