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Article

HMGA1-Regulating microRNAs Let-7a and miR-26a are Downregulated in Human Seminomas

24 Apr 2020

Abstract excerpt

Background: Recent studies have underlined HMGA protein’s key role in the onset of testicular germ cell tumors, where HMGA1 is differently expressed with respect to the state of differentiation, suggesting its fine regulation as master regulator in testicular tumorigenesis. Several studies have highlighted that the HMGA1 transcript is strictly regulated by a set of inhibitory microRNAs. Thus, the aim of this...

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PMID: 32344629
DOI: 10.3390/ijms21083014

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