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Article

Implication of alterations in Parkin gene among North Indian patients with colorectal cancer.

The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology - 1 Mar 2020

Tiwari Raj Ranjan, Wahabi Khushnuma, Perwez Ahmad, Bhat Zafar Iqbal, Hasan Syed Shamimul, Saluja Sundeep Singh, Rizvi Moshahid Alam

Abstract excerpt

BACKGROUND/AIMS: Alterations in Parkin (PRKN) have been described in many cancers; however, the molecular mechanism that contributes to loss of Parkin expression in colorectal cancer (CRC) remains unclear. The aim of this study was to investigate the involvement of PRKN mutation and loss of heterozygosity (LOH) in loss of Parkin expression. To understand the role of PRKN in cancer progression, we also evaluated...

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Identifiers

PMID: 32343233
DOI: 10.5152/tjg.2020.18823
PMCID: PMC7197922

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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