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Pullulan biosynthesis in yeast-like fungal cells is regulated by the transcriptional activator Msn2 and cAMP-PKA signaling pathway.

International journal of biological macromolecules - 15 Aug 2020

Yang Guang, Liu Guang-Lei, Wang Shu-Jun, Chi Zhen-Ming, Chi Zhe

Abstract excerpt

Pullulan is an important polysaccharide. Although its synthetic pathway in Aureobasidium melanogenum has been elucidated, the mechanism underlying its biosynthesis as regulated by signaling pathway and transcriptional regulator is still unknown. In this study, it was found that the expression of the UGP1 gene encoding UDPG-pyrophosphorylase (Ugp1) and other genes which were involved in pullulan biosynthesis was...

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PMID: 32339573
DOI: 10.1016/j.ijbiomac.2020.04.174

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