Article
Regulation of glycogen metabolism by the CRE-1, RCO-1 and RCM-1 proteins in Neurospora crassa. The role of CRE-1 as the central transcriptional regulator.
Fungal genetics and biology : FG & B - 1 Apr 2015
Cupertino Fernanda Barbosa, Virgilio Stela, Freitas Fernanda Zanolli, Candido Thiago de Souza, Bertolini Maria Célia
Abstract excerpt
The transcription factor CreA/Mig1/CRE-1 is a repressor protein that regulates the use of alternative carbon sources via a mechanism known as Carbon Catabolite Repression (CCR). In Saccharomyces cerevisiae, Mig1 recruits the complex Ssn6-Tup1, the Neurospora crassa RCM-1 and RCO-1 orthologous proteins, respectively, to bind to promoters of glucose-repressible genes. We have been studying the regulation of...
Topics
- Activating Transcription Factor 2
- Carbon
- Fungal Proteins
- Glycogen
- Glycogen Synthase
- Mutation
- Neurospora crassa
- Phosphorylation
- Promoter Regions, Genetic
- Repressor Proteins
- Transcription Factors