Characterization of NpgA, a 4'-phosphopantetheinyl transferase of Aspergillus nidulans, and evidence of its involvement in fungal growth and formation of conidia and cleistothecia for development.

Abstract excerpt

The null pigmentation mutant (npgA1) in Aspergillus nidulans results in a phenotype with colorless organs, decreased branching growth, delayed of asexual spore development, and aberrant cell wall structure. The npgA gene was isolated from A. nidulans to investigate these pleiomorphic phenomena of npgA1 mutant. Sequencing analysis of the complementing gene indicated that it contained a 4'-phosphopantetheinyl...

Topics

• Adenosine Diphosphate
• Aspergillus nidulans
• Bacterial Proteins
• Cell Wall
• Fungal Proteins
• Gene Expression Regulation, Fungal
• Mutation
• Phenotype
• Pigmentation
• Reproduction, Asexual