Article
Genetic polymorphisms as non-modifiable susceptibility factors to laryngeal cancer.
Bioscience reports - 29 May 2020
Escalante Paula, Barría Tamara, Cancino Miguel, Rahal Maritza, Cerpa Leslie, Sandoval Christopher, Molina-Mellico Sebastian, Suárez Marcelo, Martínez Matias, Cáceres Dante Daniel, Quiñones Luis Abel, Varela Nelson Miguel
Abstract excerpt
Laryngeal squamous cell carcinoma (LSCC) is a highly disabling disease to the patient, affecting speech, swallowing and respiratory skills. Smoking and alcohol abuse are principal risk factors linked to this disease. Genetic factors can be involved in carcinogenesis by controlling the cell cycle, cell survival, angiogenesis, and invasiveness. Single nucleotide polymorphisms (SNPs) involving specific genes could...
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