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MicroRNA-21 as a regulator of human cumulus cell viability and its potential influence on the developmental potential of the oocyte

25 Apr 2020

Abstract excerpt

MicroRNA-21 is expressed in bovine, murine, and human cumulus cells with its expression in murine and bovine cumulus cells correlated with oocyte developmental potential. The aim of this study was to assess the relationship between cumulus cell MIR-21 and human oocyte developmental potential. These studies revealed that both the immature and mature forms of MicroRNA-21 (MIR-21-5p) were elevated in cumulus cells...

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PMID: 32333014
DOI: 10.1093/biolre/ioaa058

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