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MicroRNAs: new candidates for the regulation of the human cumulus–oocyte complex

30 Jul 2013

Abstract excerpt

STUDY QUESTION: What is the expression pattern of microRNAs (miRNAs) in human cumulus-oocyte complexes (COCs)? SUMMARY ANSWER: Several miRNAs are enriched in cumulus cells (CCs) or oocytes, and are predicted to target genes involved in biological functions of the COC. WHAT IS KNOWN ALREADY: The transcriptional profiles of human MII oocytes and the surrounding CCs are known. However, very limited data are...

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PMID: 23904466
DOI: 10.1093/humrep/det321

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