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Genetic trajectory and immune microenvironment of lung-specific oligometastatic colorectal cancer

24 Apr 2020

Abstract excerpt

Genetics and immunologic dynamics pushing the evolution of colorectal cancer (CRC) from the primary tumor to the metastases are largely unknown; cancer heterogeneity makes challenging both therapy and mechanistic studies. We selected patients developing CRC with lung-limited metastatic disease as only illness during their life in order to find any relevant genotype-phenotype relationship. Analysis of 523...

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PMID: 32332709
DOI: 10.1038/s41419-020-2480-6

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