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Article

Volumetric analysis of IDH-mutant lower-grade glioma: a natural history study of tumor growth rates before and after treatment.

Neuro-oncology - 18 Dec 2020

Huang Raymond Y, Young Robert J, Ellingson Benjamin M, Veeraraghavan Harini, Wang Wei, Tixier Florent, Um Hyemin, Nawaz Rasheed, Luks Tracy, Kim John, Gerstner Elizabeth R, Schiff David, Peters Katherine B, Mellinghoff Ingo K, Chang Susan M, Cloughesy Timothy F, Wen Patrick Y

Abstract excerpt

BACKGROUND: Lower-grade gliomas (LGGs) with isocitrate dehydrogenase 1 and/or 2 (IDH1/2) mutations have long survival times, making evaluation of treatment efficacy difficult. We investigated the volumetric growth rate of IDH mutant gliomas before and after treatment with established glioma therapies to determine whether a significant change in growth rate could be documented and perhaps be used in the future to...

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Identifiers

PMID: 32328652
DOI: 10.1093/neuonc/noaa105
PMCID: PMC7746936

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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