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Article

Perfusion, diffusion, and anatomical MRI characteristics of pathologically confirmed malignant transformation in IDH-mutant gliomas.

Neuro-oncology - 1 Dec 2025

Cho Nicholas S, Le Viên Lam, Teraishi Ashley, Liu Vicki, Sanvito Francesco, Telesca Donatello, Nakajo Masanori, Wang Chencai, Oshima Sonoko, Eldred Blaine S C, Yao Jingwen, Nghiemphu Phioanh L, Salamon Noriko, Cloughesy Timothy F, Lai Albert, Ellingson Benjamin M

Abstract excerpt

BACKGROUND: This study explored MRI characteristics at the time of tumor progression to study pathologically confirmed MT in IDHm 1p/19q-intact astrocytomas (IDHm-A) and IDHm 1p/19q-co-deleted oligodendrogliomas (IDHm-O). METHODS: N = 64 patients with initial pathological grade 2 IDH-mutant glioma diagnosis who underwent repeated tissue sampling and were classified as pathologically confirmed MT (n = 35) or...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40888039
DOI: 10.1093/neuonc/noaf171
PMCID: PMC12916721

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