Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identifying gene-environment interactions on the efficacy of folic acid therapy for hyperhomocysteinemia based on prediction model.

Nutrition research (New York, N.Y.) - 1 May 2020

Zhao Qinglin, Li Dankang, Huang Xiaowen, Ren Bingnan, Yue Limin, Du Binghui, Zhang Chengda, Zhang Weidong

Abstract excerpt

Various genetic and environmental factors or their interactions may result in the failure of folic acid therapy for hyperhomocysteinemia (HHcy). We hypothesized that an optimal predictive model of gene-environment interactions could be constructed to predict the efficacy of folic acid therapy in HHcy. A prospective cohort study of 638 HHcy patients was performed. The patients were treated with oral folic acid (5...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Coronary Disease
Share to Folic Acid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Homocysteine

Share to Hyperhomocysteinemia

Share to Machine Learning

Share to Models, Theoretical

Share to Stroke

Share to Treatment Failure

Source

Identifiers

PMID: 32320840
DOI: 10.1016/j.nutres.2020.03.001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identifying gene-environment interactions on the efficacy of folic acid therapy for hyperhomocysteinemia based on prediction model.PMID 32320840Read ↗

Using the optimal method-explained variance weighted genetic risk score to predict the efficacy of folic acid therapy to hyperhomocysteinemia.Semantic proximity Read ↗

Combining genetic risk score with artificial neural network to predict the efficacy of folic acid therapy to hyperhomocysteinemia.Semantic proximity Read ↗

The effect of multiple single nucleotide polymorphisms in the folic acid pathway genes on homocysteine metabolism.Semantic proximity Read ↗

Genetic polymorphisms of key enzymes in folate metabolism affect the efficacy of folate therapy in patients with hyperhomocysteinaemia.Semantic proximity Read ↗

CBS gene polymorphism and promoter methylation-mediating effects on the efficacy of folate therapy in patients with hyperhomocysteinemia.Semantic proximity Read ↗

Folate Deficiency and Gene Polymorphisms of MTHFR, MTR and MTRR Elevate the Hyperhomocysteinemia Risk.Semantic proximity Read ↗

MTHFR Gene and Serum Folate Interaction on Serum Homocysteine Lowering: Prospect for Precision Folic Acid Treatment.Semantic proximity Read ↗

MTHFR C677T gene polymorphism in patients with coronary heart disease and hypertension treated with enalapril and folic acid: implications for prognosis.Semantic proximity Read ↗

Conditional Inference Tree for Multiple Gene-Environment Interactions on Myocardial Infarction.Semantic proximity Read ↗

Genetic and epigenetic regulation of BHMT is associated with folate therapy efficacy in hyperhomocysteinaemia.Semantic proximity Read ↗

Association between Micronutrients and Hyperhomocysteinemia: A Case-Control Study in Northeast China.Semantic proximity Read ↗

Neuro-fuzzy model of homocysteine metabolism.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.