Article
The Genetic Requirements for Pentose Fermentation in Budding Yeast.
G3 (Bethesda, Md.) - 7 Jun 2017
Mittelman Karin, Barkai Naama
Abstract excerpt
Cells grow on a wide range of carbon sources by regulating substrate flow through the metabolic network. Incoming sugar, for example, can be fermented or respired, depending on the carbon identity, cell type, or growth conditions. Despite this genetically-encoded flexibility of carbon metabolism, attempts to exogenously manipulate central carbon flux by rational design have proven difficult, suggesting a robust...
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