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Article

Multi-Locus Models to Address Hb F Variability in Portuguese β-Thalassemia Carriers.

Hemoglobin - 1 Mar 2020

Manco Licínio, Bento Celeste, Relvas Luís, Cunha Elisabete, Pereira Janet, Moreira Valeria, Alvarez Manuela, Maia Tabita, Ribeiro M Letícia

Abstract excerpt

Hb F production is under the influence of major quantitative trait loci (QTL). The present study aims: i) to replicate the association with Hb F for representative genetic variants in the three major Hb F QTLs in a Portuguese sample of β-thalassemia (β-thal) carriers; and ii) to test different genetic multi-locus models to account for the genetic component of Hb F variation. A population sample of 79 Portuguese...

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Identifiers

PMID: 32319326
DOI: 10.1080/03630269.2020.1753766

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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