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Article

Heterogeneity of Stemlike Circulating Tumor Cells in Invasive Breast Cancer.

International journal of molecular sciences - 16 Apr 2020

Savelieva Olga E, Tashireva Liubov A, Kaigorodova Evgeniya V, Buzenkova Angelina V, Mukhamedzhanov Rustam Kh, Grigoryeva Evgeniya S, Zavyalova Marina V, Tarabanovskaya Natalia A, Cherdyntseva Nadezhda V, Perelmuter Vladimir M

Abstract excerpt

The presence of stem and epithelial-mesenchymal-transition (EMT) features in circulating tumor cells (CTCs) determines their invasiveness, adaptability to the microenvironment, and resistance to proapoptotic signals and chemotherapy. It also allows them to fulfil the role of metastatic "seeds". We evaluated the heterogeneity of stem CTCs by their CD44, ALDH1, and CD133 expression depending on N-cadherin...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32316333
DOI: 10.3390/ijms21082780
PMCID: PMC7216207

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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