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Article

Lack of Targetable FGFR2 Fusions in Endemic Fluke-Associated Cholangiocarcinoma

21 Apr 2020

Abstract excerpt

PURPOSE Cholangiocarcinoma (CCA) remains a disease with poor prognosis and limited therapeutic options. Identification of driver genetic alterations may lead to the discovery of more effective targeted therapies. CCAs harboring FGFR2 fusions have recently demonstrated promising responses to FGFR inhibitors, highlighting their potential relevance as predictive biomarkers. CCA incidence is high in the northeast of...

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Share to Cholangiocarcinoma and Gallbladder Cancer Studies
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PMID: 32315234
DOI: 10.1200/go.20.00030

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