Article
An unusual variant glycophorin expressing protease-resistant M antigen encoded by the GYPB-E(2-4)-B hybrid gene.
Vox sanguinis - 1 Oct 2020
Tsuneyama Hatsue, Isa Kazumi, Watanabe-Okochi Naoko, Ogasawara Kenichi, Uchikawa Makoto, Satake Masahiro
Abstract excerpt
BACKGROUND AND OBJECTIVES: MNS is a highly polymorphic blood group comprising 49 antigens recognized by International Society of Blood Transfusion, some of which may have been generated by genomic recombination among the closely linked genes GYPA, GYPB and GYPE. The GYPE gene has an almost identical sequence to GYPA*01 allele in exon 2 (99% homology), which accounts for M antigen. We investigated an unusual...
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