Article
Anti-U-like as an alloantibody in S-s-U- and S-s-U+(var) black people.
Transfusion - 1 Mar 2012
Peyrard Thierry, Lam Yin, Saison Carole, Arnaud Lionel, Babinet Jérôme, Rouger Philippe, Bierling Philippe, Janvier Daniel
Abstract excerpt
BACKGROUND: S, s, and U antigens belong to the MNS system. They are carried by glycophorin B (GPB), encoded by GYPB. Black people with the low-prevalence S-s- phenotype, either U- or U+(var), can make a clinically significant anti-U. Anti-U-like, a cold immunoglobulin G autoantibody quite commonly observed in S-s+U+ black persons, was previously described to be nonreactive with ficin-, α-chymotrypsin-, and...
Topics
- Adolescent
- Adult
- Autoantibodies
- Black People
- Female
- Genotype
- Glycophorins
- Hemagglutination
- Humans
- Immunoglobulin G
- Isoantibodies
- MNSs Blood-Group System