Article
A novel GYPB-A-B hybrid gene responsible for Ss and MN typing discrepancies.
Transfusion - 1 Nov 2015
Willemetz Alexandra, Nataf Joelle, Peyrard Thierry, Arnaud Lionel
Abstract excerpt
BACKGROUND: Transfusion support of S-s- patients is very challenging but can now be alleviated by genotyping mutations in the GYPB gene to predict their U- or U+(var) phenotype. However, the phenotype predicted by genotyping does not always correspond to the observed phenotype of red blood cells (RBCs), which requires further investigation to avoid such a typing discrepancy in the future. In this study, we...
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