Article
Novel hybrid genes and a splice site mutation encoding the Sta antigen among Japanese blood donors.
Vox sanguinis - 1 Nov 2020
Watanabe-Okochi Naoko, Tsuneyama Hatsue, Isa Kazumi, Sasaki Kana, Suzuki Yumi, Yabe Ryuichi, Tsuno Nelson-Hirokazu, Nakajima Kazunori, Ogasawara Kenichi, Uchikawa Makoto
Abstract excerpt
BACKGROUND: The low-incidence antigen Sta of the MNS system is usually associated with the GP(B-A) hybrid molecule, which carries the 'N' antigen at the N terminus. The GP(A-A) molecule with trypsin-resistant M antigen has been found in a few St(a+) individuals. MATERIALS AND METHODS: Among Japanese blood donors, we screened 24 292 individuals for the presence of St(a+) with trypsin-resistant 'N' antigen and...
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