Sixty years of antibodies to MNS system hybrid glycophorins: what have we learned?

doi:10.1016/j.tmrv.2010.11.003

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Sixty years of antibodies to MNS system hybrid glycophorins: what have we learned?

Transfusion medicine reviews - 1 Apr 2011

Heathcote Damien J, Carroll Timothy E, Flower Robert L

Abstract excerpt

The MNS system was the second blood group system discovered and at least 16 of the 46 antigens in the MNS system result from genetic recombination, producing a hybrid glycophorin. The incidence of these hybrid glycophorins is highest in East Asian populations. MNS system antigens defined by hybrid glycophorins are immunogenic with alloimmune IgG responses developing after transfusion or pregnancy; with reports...

Topics

Anemia, Hemolytic
Antibodies, Anti-Idiotypic
Antigens
Blood Transfusion
Ethnicity
Female
Glycophorins
Humans
Immunoglobulin G
MNSs Blood-Group System
Malaria
Male
Models, Genetic
Phenotype
Pregnancy
Recombination, Genetic

Source

Open in PubMed

Identifiers

PMID: 21345645
DOI: 10.1016/j.tmrv.2010.11.003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics