Article
Genotyping for Glycophorin GYP(B-A-B) Hybrid Genes Using a Single Nucleotide Polymorphism-Based Algorithm by Matrix-Assisted Laser Desorption/Ionisation, Time-of-Flight Mass Spectrometry.
Molecular biotechnology - 1 Oct 2016
Wei Ling, Lopez Genghis H, Ji Yanli, Condon Jennifer A, Irwin Darryl L, Luo Guangping, Hyland Catherine A, Flower Robert L
Abstract excerpt
The genetic basis for five GP(B-A-B) MNS system hybrid glycophorin blood group antigens results from rearrangement between the homologous GYPA and GYPB genes. Each hybrid glycophorin displays a characteristic profile of antigens. Currently, no commercial serological reagents are currently available to serologically type for these antigens. The aim of this study was to develop a single nucleotide polymorphism...
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