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Article

Novel single-nucleotide change in GYP*A in a person who made an alloantibody to a new high-prevalence MNS antigen called ENEV.

Transfusion - 1 Apr 2010

Velliquette Randall W, Hu Zong, Lomas-Francis Christine, Hue-Roye Kim, Allen Jean L, Mirabella Donna, Reid Marion E

Abstract excerpt

BACKGROUND: Alloantibodies that define some high-prevalence MNS antigens are made by people with glycophorin A (GPA) altered by a single-amino-acid change or replacement of amino acids from part of the Pseudoexon 3 of GYP*B. The finding of a patient whose plasma contained a novel alloanti-En(a)FR prompted this study. RESULTS: The patient's serum contained an alloantibody to a high-prevalence antigen, resistant to...

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Identifiers

PMID: 20003059
DOI: 10.1111/j.1537-2995.2009.02522.x

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