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Article

Inhibition of endoplasmic reticulum stress ameliorates cardiovascular injury in a rat model of metabolic syndrome.

Journal of molecular and cellular cardiology - 1 Jun 2020

Radwan Eman, Bakr Marwa H, Taha Salma, Sayed Sally A, Farrag Alshaimaa A, Ali Maha

Abstract excerpt

Metabolic (Met) syndrome is characterized by hypertension, insulin resistance and dyslipidaemia with high risk of cardiovascular disease. Endoplasmic reticulum (ER) stress is a key contributor in the pathogenesis of Met syndrome. The current study investigates the effect of Tauroursodeoxycholate (TUDCA), an ER stress inhibitor, on Met syndrome-induced cardiovascular complications and the possible underlying...

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Source

Identifiers

PMID: 32311415
DOI: 10.1016/j.yjmcc.2020.04.020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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