Article
Constitutive TSH receptor activation as a hallmark of thyroid autonomy.
Endocrine - 1 May 2020
Führer Dagmar
Abstract excerpt
Since its cloning more than 30 years ago, the thyrotropin receptor (TSHR) has emerged as a pivotal player in thyroid physiology and pathophysiology. In particular, hyperthyroidism due to autoimmune disease or thyroid autonomy is linked with TSHR activation via autoantibodies or mutations respectively. This review summarises clinical aspects of constitutive TSH receptor activation by naturally occurring somatic or...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
