Article
The TSH receptor and thyroid diseases.
Bailliere's clinical endocrinology and metabolism - 1 Jan 1996
Paschke R, Van Sande J, Parma J, Vassart G
Abstract excerpt
Recent advances in the understanding of the molecular biology of the TSH receptor have had a considerable impact on several aspects of thyroidology. The identification and functional characterization of mutations in the TSH receptor gene which constitutively activate the TSH receptor in the absence of its ligand provide an explanation for the molecular mechanism which is most likely responsible for the majority...
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