Article
Circadian Rhythms of Endothelial Nitric Oxide Synthase and Toll-like Receptors 2 Production in Females with Rheumatoid Arthritis Depending on NOS3 Gene Polymorphism.
Reviews on recent clinical trials - 1 Jan 2020
Zaichko Kateryna, Zaichko Nataliia, Maievskyi Oleksandr, Korotkyi Oleksandr, Falalyeyeva Tetyana, Fagoonee Sharmila, Pellicano Rinaldo, Abenavoli Ludovico, Stanislavchuk Mykola
Abstract excerpt
BACKGROUND: Rheumatoid Arthritis (RA) is an autoimmune polygenic disease characterized by rapid disability progression and high prevalence. Progression of RA is closely associated with chronobiological changes in the production of some hormones and inflammatory mediators, influencing the disease course and therapy efficacy. The main pathogenetic mechanism of RA is angiogenesis, which is controlled by biological...
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