Article
Effect of Peroxisome Proliferator-Activated Receptor-γ Coactivator-1 Alpha Variants on Spontaneous Clearance and Fibrosis Progression during Hepatitis C Virus Infection in Moroccan Patients.
Virologica Sinica - 1 Oct 2020
ElFihry Raouia, Elmessaoudi-Idrissi Mohcine, Jadid Fatima-Zahra, Zaidane Imane, Chihab Hajar, Tahiri Mohamed, Kabine Mostafa, Badre Wafaa, Chemin Isabelle, Marchio Agnes, Pineau Pascal, Ezzikouri Sayeh, Benjelloun Soumaya
Abstract excerpt
Hepatitis C virus (HCV) is still one of the main causes of liver disease worldwide. Metabolic disorders, including non-alcoholic fatty liver disease (NAFLD), induced by HCV have been shown to accelerate the progression of fibrosis to cirrhosis and to increase the risk of hepatocellular carcinoma. An optimal peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPARGC1A) activity is crucial to...
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