Article
CRF01_AE subtype is associated with X4 tropism and fast HIV progression in Chinese patients infected through sexual transmission.
AIDS (London, England) - 20 Feb 2014
Li Yijia, Han Yang, Xie Jing, Gu Lijun, Li Wenjuan, Wang Huanling, Lv Wei, Song Xiaojing, Li Yanling, Routy Jean-Pierre, Ishida Takaomi, Iwamoto Aikichi, Li Taisheng
Abstract excerpt
BACKGROUND: The molecular epidemiology of the HIV-1 CRF01_AE subtype as a risk factor for fast HIV-1 progression remains poorly understood. METHODS: We analyzed HIV-1 tropism by utilizing samples from 201 treatment-naive patients in our multicenter cohort (12 research centers in different provinces of China). Tropism was determined by V3 loop sequencing. Data from 235 treatment-naive patients infected sexually...
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