CRF07_BC is associated with slow HIV disease progression in Chinese patients.

doi:10.1038/s41598-022-07518-4

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CRF07_BC is associated with slow HIV disease progression in Chinese patients.

Scientific reports - 8 Mar 2022

Ye Jingrong, Chen Jing, Wang Juan, Wang Yuncong, Xing Hui, Yu Fengting, Liu Lifeng, Han Yang, Huang Huihuang, Feng Yi, Ruan Yuhua, Zheng Minna, Lu Xinli, Guo Xiaoli, Yang Hong, Guo Qi, Lin Yi, Wu Jianjun, Wu Shouli, Tang Yilong, Sun Xiaoguang, Zou Xiaobai, Yu Guolong, Li Jianjun, Zhou Quanhua, Su Ling, Zhang Lincai, Gao Zhan, Xin Ruolei, He Shufang, Xu Conghui, Hao Mingqiang, Hao Yinxiao, Ren Xianlong, Li Jie, Bai Lishi, Jiang Tianjun, Zhang Tong, Shao Yiming, Lu Hongyan

Abstract excerpt

HIV subtypes convey important epidemiological information and possibly influence the rate of disease progression. In this study, HIV disease progression in patients infected with CRF01_AE, CRF07_BC, and subtype B was compared in the largest HIV molecular epidemiology study ever done in China. A national data set of HIV pol sequences was assembled by pooling sequences from public databases and the Beijing HIV...

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PMID: 35260599
DOI: 10.1038/s41598-022-07518-4
PMCID: PMC8904811

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