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Cross-talk between cancer stem cells and immune cells: potential therapeutic targets in the tumor immune microenvironment

21 Feb 2023

Abstract excerpt

Ongoing research has revealed that the existence of cancer stem cells (CSCs) is one of the biggest obstacles in the current cancer therapy. CSCs make an influential function in tumor progression, recurrence and chemoresistance due to their typical stemness characteristics. CSCs are preferentially distributed in niches, and those niche sites exhibit characteristics typical of the tumor microenvironment (TME). The...

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PMID: 36810098
DOI: 10.1186/s12943-023-01748-4

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