Molecular Epidemiology of Mycobacterium tuberculosis To Describe the Transmission Dynamics Among Inuit Residing in Iqaluit Nunavut Using Whole-Genome Sequencing.

doi:10.1093/cid/ciaa420

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Article

Molecular Epidemiology of Mycobacterium tuberculosis To Describe the Transmission Dynamics Among Inuit Residing in Iqaluit Nunavut Using Whole-Genome Sequencing.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 15 Jun 2021

Alvarez Gonzalo G, Zwerling Alice A, Duncan Carla, Pease Christopher, Van Dyk Deborah, Behr Marcel A, Lee Robyn S, Mulpuru Sunita, Pakhale Smita, Cameron D William, Aaron Shawn D, Patterson Michael, Allen Jean, Sullivan Kathryn, Jolly Anne, Sharma Meenu K, Jamieson Frances B

Abstract excerpt

BACKGROUND: In the last decade, tuberculosis (TB) incidence among Inuit in the Canadian Arctic has been rising. Our aim was to better understand the transmission dynamics of TB in this remote region of Canada using whole-genome sequencing. METHODS: Isolates from patients who had culture-positive pulmonary TB in Iqaluit, Nunavut, between 2009 and 2015 underwent whole-genome sequencing (WGS). The number of...

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PMID: 32293676
DOI: 10.1093/cid/ciaa420
PMCID: PMC8204784

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