Article
Genotyping and Whole-Genome Sequencing to Identify Tuberculosis Transmission to Pediatric Patients in British Columbia, Canada, 2005-2014.
The Journal of infectious diseases - 24 Aug 2018
Guthrie Jennifer L, Delli Pizzi Andy, Roth David, Kong Clare, Jorgensen Danielle, Rodrigues Mabel, Tang Patrick, Cook Victoria J, Johnston James, Gardy Jennifer L
Abstract excerpt
Background: Tuberculosis (TB) in children is often an indicator of recent transmission. Genotyping and whole-genome sequencing (WGS) can enhance pediatric TB investigations by confirming or refuting transmission events. Methods: Mycobacterium tuberculosis isolates from all pediatric patients <18 years with culture-confirmed TB in British Columbia (BC) from 2005 to 2014 (n = 49) were genotyped by Mycobacterial...
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